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February 21, 2006

NORML: Cannabinoids Enhance Analgesic Effects Of Anti-Inflammatory Drugs, Study Says

Posted by Gary Storck
February 21, 2006

NORML's Weekly News Bulletin click here, always a great source for the latest developments in cannabis, contained an item about medical cannabis in the February 16, 2006 edition.

Studies have already shown a synergistic effect between opioids and cannabis click here, allowing patients to use less opiate medication but gain superior relief. The new study is more good news for chronic pain sufferers -- cannabis also works synergistically with NSAID pain relievers like ibuprofen.

Cannabinoids Enhance Analgesic Effects Of Anti-Inflammatory Drugs, Study Says

February 16, 2006 - Ankara, Turkey

Ankara, Turkey: Cannabinoids, when administered in combination with non-steroidal anti-inflammatory drugs (NSAIDS), produce a synergistic analgesic effect, according to preclinical data published in the February issue of the journal Anesthesia & Analgesia.

A research team at the Trakya University in Turkey investigated the analgesic interaction between cannabinoids and NSAIDS in mice. "Analysis showed additive interactions between [cannabinoids] and [NSAIDS] when they were co-administered systematically in an inflammatory visceral pain model," investigators concluded. "The combination of cannabinoids and NSAIDS may have utility in the pharmacotherapy of pain."

Currently, a research team at the San Francisco General Hospital in California is evaluating the effectiveness of inhaled cannabis when used as an adjunctive therapy in combination with opioids to treat persistent cancer pain. The findings of that clinical trial are expected to be published later this year.

For more information, please contact Paul Armentano, NORML Senior Policy Analyst, at (202) 483-5500. Full text of the Turkish study, "The additive antinociceptive interaction between WIN 55,212-2, a cannabinoid agonist, and Ketorolac," appears in the journal Anesthesia & Analgesia.

Posted by Gary at February 21, 2006 10:14 AM

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